(Cat. No. 202719) Human 2C6 scFv Recombinant Antibody, hIgGC, 100 μg
Beschreibung
Description
1 F5 RHC contains a specifically mutated human IgG1 Fc reg ion which results in a reduction in binding to Fc receptors 1 F5 RHC specifically binds to the scFv region of a CD 20 specific human monoclonal antibody (mAb, clone 2C6 CD20 (cluster of differentiate 20) is a protein that is expressed on the surface of B cells, starting at the pre B cell stage and also on mature B cells in the bone marrow and in the periphery. CD20 is not expressed on hematopoietic stem cells, pro B cell s, or normal plasma cells. T he scFv region of 2C6 has been used to develop CD 20 specific chimeric antigen receptor (CAR) T cells utilized in clinical
Specification
- Size: 100 μg
- Concentration: 1.0 mg/mL
- Istoype: Rabbit IgG, κ light chain
- Clone: 1F5 RHC
- Antibody types: Primary antibodies, recombinant antibodies
- Immunogen: scFv region of a CD20-specific human mAb clone 2C6
- Reactivity: Human
- Storage buffer: PBS, pH 7.4
- Preservative: None
Preparation and Storage
- Shipped at 2 8°C.
- Store at 2 8°C for short term (1 month).
- Store at 20°C in small aliquots for long term storage.
- Avoid freeze/thaw cycle.
- The monoclonal antibody was purified by Protein A.
Product Notices
- 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
- Conditions: The information disclosed herein is not to be construed as a recommendation to use the above product in vio lation of any p atents. BioSwan will not be held responsible for patent infringement or other violations that may occur with the use of our products. Purchase does not include or carry any right to resell or transfer this product either as a stand alone product or as a co mponent of another product. Any use of this product other than the permitted use without the express written authorization of BioSwan Company is strictly prohibited. product other than the permitted use without the express written authorization of BioSwan Company is strictly prohibited. For Research Use Only. Not for use in diagnostic or therapeutic procedures. Not for resale For Research Use Only. Not for use in diagnostic or therapeutic procedures. Not for resales.s. BioSwan, the BioSwan Logo and all other trademarks are property of BioSwan Laboratories, Co., Ltd.. BioSwan, the BioSwan Logo and all other trademarks are property of BioSwan Laboratories, Co., Ltd..