(Cat. No. 212002) Rabbit Anti-LCAR-B38M Monoclonal Antibody, Alexa Fluor 647, 100 tests

1.799,00 €
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Beschreibung

Description


38-1H2 is a specific antibody that binds precisely to two tandem VHH sequences of LCAR-B38M. These sequences are designed to target two epitopes of the B-cell maturation antigen (BCMA). BCMA is a protein expressed selectively by B-lineage cells, including both normal and malignant plasma cells in multiple myeloma. Ciltacabtagene autoleucel, also known as cilta-cel or Carvykti, is a gene-edited autologous CAR T-cell therapy. It utilizes LCAR and B38M to effectively recognize BCMA-positive cells.


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Specification


  • Size: 100 tests
  • Recommended Vol. per test: 1μl
  • Antibody Types: Monoclonal
  • Antibody Format: Whole IgG
  • Clone: 38-1H2
  • Immunogen: Two Tandem VHH Sequences of LCAR-B38M
  • Conjugate: Alexa Fluor 647
  • Excitation/Emission Max: 651/667nm
  • Host species: Rabbit
  • Application: Flow Cytometry
  • Storage buffer: Aqueous buffered solution containing protein stabilizer and ≤0.05% ProClin 300



Preparation and Storage

  • Store undiluted at 2-8°C.
  • Avoid prolonged exposure to light.
  • Avoid freeze/thaw cycle of the reagent.
  • The monoclonal antibody was purified by Protein A.
  • The antibody was conjugated with Alexa Fluor 647 under optimum conditions, and unincorporated dye was removed.


Product Notices

  • Since applications vary, each investigator should titrate the reagent to obtain optimal results.
  • Caution: Antibody solutions containing ProClin 300 should be handled with care. Do not take internally and avoid all contact with the skin, mucosa and eyes.