(Cat. No. 500019) Rabbit Anti-Mouse FMC63 scFv (R19P) 100 µg

(Cat. No. 500019) Rabbit Anti-Mouse FMC63 scFv (R19P) 100 µg

300,00 €

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Beschreibung

Description

The rabbit polyclonal antibody R19 specifically binds to the scFv region of a CD19-specific mouse monoclonal antibody (mAb, clone FMC63). CD19 antigen is a B-cell specific cell surface antigen, which is expressed in all B-cell lineage malignancies and normal B-cells. The scFv region of FMC63 has been used to develop CD19-specific chimeric antigen receptor (CAR) T cells utilized in clinical trials.


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Specification


  • Host species: Rabbit
  • Antibody type: Polyclonal
  • Immunogen: scFv region of a CD19-specific mouse mAb clone FMC63
  • Reactivity: Mouse
  • Application: FCM
  • Storage buffer: Aqueous buffered solution containing protein stabilizer and ≤0.03% sodium azide



Preparation and Storage

  • Shipped at 4°C
  • Store at 4°C short term (1-2 weeks)
  • Store at -20°C in small aliquots for long term storage
  • Avoid freeze/thaw cycle
  • The polyclonal antibody was purified by Protein A


Product Notices


  • Since applications vary, each investigator should titrate the reagent to obtain optimal results.
  • Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.